BioInformatics:Algorithms and Applications

Overview

Syllabus 12

1. Week 1
   • Concepts and importance of Bioinformatics
   • Complexities in biological systems
   • DNA sequence analysis
   • Sequence based parameters
   • Database
   • Database categories
2. Week 2
   • Protein structure and function
   • Protein structure and function II
   • Protein sequence databases
   • Protein sequence databases II
   • Pairwise alignment
   • Pairwise alignment II
   • Uniprot Demo
3. Week 3
   • Sequence alignment
   • Sequence alignment II
   • Sequence alignment: Online resources
   • Sequence alignment: Online resources II
   • Conservation score
   • Conservation score II
   • Blast Demo
4. Week 4
   • Phylogenetic trees
   • Phylogenetic trees II
   • Protein sequence analysis
   • Protein sequence analysis II
   • Hydrophobicity profiles
   • Patterns and PSSM profiles
5. Week 5
   • Construction of Non-redundant datasets I
   • Non-redundant datasets II
   • Protein secondary structure
   • Secondary structure prediction I
   • Secondary structure prediction II
   • Secondary structure prediction III
6. Week 6
   • Protein tertiary structure I
   • Protein tertiary structure II
   • Protein structure analysis - I
   • Protein structure analysis II
   • Protein structure analysis III
   • Demo: PDB or Pymol or PDBParam
7. Week 7
   • Protein structure analysis - IV
   • Protein structure prediction - I
   • Protein structure prediction - II
   • Protein stability - I
   • Protein stability - II
   • Demo: Homology Modelling
8. Week 8
   • Stabilizing residues
   • Thermodynamic database
   • Stability of proteins upon mutations
   • Stability of proteins upon mutations II
   • Demo: ProTherm
9. Week 9
   • Protein folding rate I
   • Protein folding rate II
   • Protein interactions I
   • Protein interactions II
   • Computer aided drug design I
10. Week 10
    • Computer aided drug design - II
    • Virtual screening - I
    • Virtual screening - II
    • QSAR - I
    • QSAR - II
11. Week 11
    • Demo: Autodock
    • awk programming - I
    • awk programming - II
    • Development of algorithms - I
    • Development of algorithms - II
12. Week 12
    • Applications of bioinformatics - I
    • Applications of bioinformatics - II
    • Overview - I
    • Overview - II
    • Demo: Weka

Advantages and disadvantages

Some points apply to every course of this kind; see how we rank.

Taught by

• Prof. Michael GromihaIIT Madras